Was born at Canterbury, where his father, John Twyne, was Master of the King's School. He was educated at Oxford and Cambridge, where he studied medicine, which he afterwards practised at Lewes in Sussex. He also devoted himself to astrology, and compiled "Almanacks and Prognostications for diver Years," as well as other works. He died in 1613, at the age of 70.

[See Wood's "Athenæ Oxon."]