ZNF334
Identifiers
Aliases	ZNF334, zinc finger protein 334
External IDs	MGI: 2388656 HomoloGene: 23076 GeneCards: ZNF334
Gene location (Mouse) Chr. Chromosome 2 (mouse)[1] Band 2|2 H3 Start 165,216,184 bp[1] End 165,230,179 bp[1]
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding metal ion binding nucleic acid binding protein binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component intracellular anatomical structure nucleus Biological process regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55713 228876 Ensembl ENSG00000198185 ENSMUSG00000017667 UniProt Q9HCZ1 A2A4U6 RefSeq (mRNA) NM_001270497 NM_018102 NM_199441 NM_178411 RefSeq (protein) NP_001257426 NP_060572 NP_001340742 NP_001340743 NP_001340744 NP_001340745 NP_001340746 NP_001340747 NP_001340748 NP_001340749 NP_001340750 NP_001340751 NP_001340752 NP_001340753 NP_001340754 NP_001340755 NP_955473 NP_848498 Location (UCSC) n/a Chr 2: 165.22 – 165.23 Mb PubMed search [2] [3]
Wikidata
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Zinc finger protein 334 is a protein that in humans is encoded by the ZNF334 gene. ^[4]

Function

This gene encodes a member of the C2H2 zinc finger family. The encoded protein contains a Krueppel-associated box, fourteen C2H2 zinc finger domains, and four C2H2-type/integrase DNA-binding domains. Decreased expression of this gene may be a marker for rheumatoid arthritis. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.