ZSCAN4
Identifiers
AliasesZSCAN4, ZNF494, zinc finger and SCAN domain containing 4
External IDsOMIM: 613419 HomoloGene: 138332 GeneCards: ZSCAN4
Orthologs
SpeciesHumanMouse
Entrez

201516

n/a

Ensembl

ENSG00000180532

n/a

UniProt

Q8NAM6

n/a

RefSeq (mRNA)

NM_152677
NM_001384833

n/a

RefSeq (protein)

NP_689890

n/a

Location (UCSC)Chr 19: 57.67 – 57.68 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Zinc finger and SCAN domain containing 4 is a protein that in humans is encoded by the ZSCAN4 gene. [3]

Function

The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture.[4]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000180532 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Entrez Gene: Zinc finger and SCAN domain containing 4". Retrieved 2017-06-05.
  4. Ko, Minoru S. H.; Wersto, Robert P.; Indig, Fred E.; Yang, Hsih-Te; Hoang, Hien G.; Carole A. Stagg; Lee, Sung-Lim; Thomas, Marshall; Nishiyama, Akira (April 2010). "Zscan4 regulates telomere elongation and genomic stability in ES cells". Nature. 464 (7290): 858–863. Bibcode:2010Natur.464..858Z. doi:10.1038/nature08882. ISSN 1476-4687. PMC 2851843. PMID 20336070.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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