Temocapril

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	C09AA14 (WHO)
Identifiers
IUPAC name 2-[(2S)-6-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-5-oxo-2-thiophen-2-yl-1,4-thiazepan-4-yl]acetic acid
CAS Number	111902-57-9
PubChem CID	71323
ChemSpider	64431
UNII	18IZ008EU6
KEGG	D08566 Y
ChEMBL	ChEMBL2110627
CompTox Dashboard (EPA)	DTXSID3048239
Chemical and physical data
Formula	C23H28N2O5S2
Molar mass	476.61 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCOC(=O)[C@H](CCc1ccccc1)NC2CS[C@@H](CN(C2=O)CC(=O)O)c3cccs3
InChI InChI=1S/C23H28N2O5S2/c1-2-30-23(29)17(11-10-16-7-4-3-5-8-16)24-18-15-32-20(19-9-6-12-31-19)13-25(22(18)28)14-21(26)27/h3-9,12,17-18,20,24H,2,10-11,13-15H2,1H3,(H,26,27)/t17-,18?,20-/m0/s1 Key:FIQOFIRCTOWDOW-DXCJPMOASA-N
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Temocapril (also known as temocaprilum [Latin]; brand name Acecol) is an ACE inhibitor. It was not approved for use in the US.

It is administered as inactive prodrug, then converted to its active metabolite, temocaprilat.

It was patented in 1984 and approved for medical use in 1994.^[1]

References