SCRG1
Identifiers
AliasesSCRG1, SCRG-1, stimulator of chondrogenesis 1
External IDsOMIM: 603163 MGI: 1328308 HomoloGene: 5269 GeneCards: SCRG1
Orthologs
SpeciesHumanMouse
Entrez

11341

20284

Ensembl

ENSG00000164106

ENSMUSG00000031610

UniProt

O75711

O88745

RefSeq (mRNA)

NM_007281
NM_001329597

NM_009136

RefSeq (protein)

NP_001316526
NP_009212

NP_033162

Location (UCSC)Chr 4: 173.38 – 173.41 MbChr 8: 57.91 – 57.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Stimulator of chondrogenesis 1 is a protein that in humans is encoded by the SCRG1 gene. [5]

Function

Scrapie-responsive gene 1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The scrapie responsive protein 1 may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus. In addition, the encoded protein can interact with bone marrow stromal cell antigen 1 (BST1) to enhance the differentiation potentials of human mesenchymal stem cells during tissue and bone regeneration. [provided by RefSeq, Jul 2016].

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000164106 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000031610 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Stimulator of chondrogenesis 1". Retrieved 2018-10-01.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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