SSR2
Identifiers
AliasesSSR2, TLAP, TRAP-BETA, TRAPB, HSD25, signal sequence receptor subunit 2
External IDsOMIM: 600867 MGI: 1913506 HomoloGene: 2369 GeneCards: SSR2
Orthologs
SpeciesHumanMouse
Entrez

6746

66256

Ensembl

ENSG00000163479

ENSMUSG00000041355

UniProt

P43308

Q9CPW5

RefSeq (mRNA)

NM_003145

NM_025448

RefSeq (protein)

NP_003136

NP_079724
NP_001343245
NP_001343246
NP_001343247
NP_001343248

Location (UCSC)Chr 1: 156.01 – 156.02 MbChr 3: 88.58 – 88.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Translocon-associated protein subunit beta also known as TRAP-beta is a protein that in humans is encoded by the SSR2 gene.[5][6]

Function

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000163479 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041355 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Chinen K, Sudo K, Takahashi E, Nakamura Y (Jul 1995). "Isolation and mapping of the human beta-signal sequence receptor gene (SSR2)". Cytogenetics and Cell Genetics. 70 (3–4): 215–7. doi:10.1159/000134036. PMID 7789174.
  6. 1 2 "Entrez Gene: SSR2 signal sequence receptor, beta (translocon-associated protein beta)".

Further reading


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