SEC24D
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesSEC24D, CLCRP2, SEC24 homolog D, COPII coat complex component
External IDsOMIM: 607186 MGI: 1916858 HomoloGene: 40986 GeneCards: SEC24D
Orthologs
SpeciesHumanMouse
Entrez

9871

69608

Ensembl

ENSG00000150961

ENSMUSG00000039234

UniProt

O94855

n/a

RefSeq (mRNA)

NM_014822
NM_001318066

NM_027135

RefSeq (protein)

NP_001304995
NP_055637

n/a

Location (UCSC)Chr 4: 118.72 – 118.84 MbChr 3: 123.06 – 123.16 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein transport protein Sec24D is a protein that in humans is encoded by the SEC24D gene.[5][6][7]

The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The role of this gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000150961 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039234 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
  6. Pagano A, Letourneur F, Garcia-Estefania D, Carpentier JL, Orci L, Paccaud JP (Apr 1999). "Sec24 proteins and sorting at the endoplasmic reticulum". J Biol Chem. 274 (12): 7833–40. doi:10.1074/jbc.274.12.7833. PMID 10075675.
  7. 1 2 "Entrez Gene: SEC24D SEC24 related gene family, member D (S. cerevisiae)".

Further reading


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