RHOJ
Identifiers
AliasesRHOJ, ARHJ, RASL7B, TC10B, TCL, ras homolog family member J
External IDsOMIM: 607653 MGI: 1931551 HomoloGene: 56894 GeneCards: RHOJ
Orthologs
SpeciesHumanMouse
Entrez

57381

80837

Ensembl

ENSG00000126785

ENSMUSG00000046768

UniProt

Q9H4E5

Q9ER71

RefSeq (mRNA)

NM_020663

NM_023275

RefSeq (protein)

NP_065714
NP_065714.1

NP_075764

Location (UCSC)Chr 14: 63.2 – 63.29 MbChr 12: 75.36 – 75.45 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Rho-related GTP-binding protein RhoJ is a protein that in humans is encoded by the RHOJ gene.[5][6]

ARHJ belongs to the Rho family of small GTP-binding proteins. Rho proteins regulate the dynamic assembly of cytoskeletal components for several physiologic processes, such as cell proliferation and motility and the establishment of cell polarity. They are also involved in pathophysiologic process, such as cell transformation and metastasis.[supplied by OMIM][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000126785 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000046768 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Vignal E, De Toledo M, Comunale F, Ladopoulou A, Gauthier-Rouviere C, Blangy A, Fort P (Dec 2000). "Characterization of TCL, a new GTPase of the rho family related to TC10 and Ccdc42". J Biol Chem. 275 (46): 36457–64. doi:10.1074/jbc.M003487200. PMID 10967094.
  6. 1 2 "Entrez Gene: RHOJ ras homolog gene family, member J".

Further reading


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