PRMT6
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPRMT6, HRMT1L6, protein arginine methyltransferase 6
External IDsOMIM: 608274 MGI: 2139971 HomoloGene: 10024 GeneCards: PRMT6
EC number2.1.1.321
Orthologs
SpeciesHumanMouse
Entrez

55170

99890

Ensembl

ENSG00000198890

ENSMUSG00000049300

UniProt

Q96LA8

Q6NZB1

RefSeq (mRNA)

NM_018137

NM_178891

RefSeq (protein)

NP_060607

NP_849222

Location (UCSC)Chr 1: 107.06 – 107.07 MbChr 3: 110.15 – 110.16 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein arginine N-methyltransferase 6 is an enzyme that in humans is encoded by the PRMT6 gene.[5][6]

Protein arginine N-methyltransferases, such as PRMT6, catalyze the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine.[supplied by OMIM][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000198890 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000049300 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Frankel A, Yadav N, Lee J, Branscombe TL, Clarke S, Bedford MT (Jan 2002). "The novel human protein arginine N-methyltransferase PRMT6 is a nuclear enzyme displaying unique substrate specificity". J Biol Chem. 277 (5): 3537–43. doi:10.1074/jbc.M108786200. PMID 11724789.
  6. 1 2 "Entrez Gene: PRMT6 protein arginine methyltransferase 6".

Further reading


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