OR2B6
Identifiers
AliasesOR2B6, OR2B1, OR2B1P, OR2B5, OR2B6P, OR5-40, OR5-41, OR6-31, dJ408B20.2, olfactory receptor family 2 subfamily B member 6
External IDsMGI: 104715 HomoloGene: 40838 GeneCards: OR2B6
Orthologs
SpeciesHumanMouse
Entrez

26212

218066

Ensembl

ENSG00000124657

ENSMUSG00000036658

UniProt

P58173

Q60890

RefSeq (mRNA)

NM_012367

NM_146542

RefSeq (protein)

NP_036499

NP_666753

Location (UCSC)Chr 6: 27.96 – 27.96 MbChr 13: 21.82 – 21.83 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2B6 is a protein that in humans is encoded by the OR2B6 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000124657 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000036658 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. S2CID 31129045.
  6. 1 2 "Entrez Gene: OR2B6 olfactory receptor, family 2, subfamily B, member 6".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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