NOX3
Identifiers
AliasesNOX3, GP91-3, MOX-2, NADPH oxidase 3
External IDsOMIM: 607105 MGI: 2681162 HomoloGene: 49435 GeneCards: NOX3
Orthologs
SpeciesHumanMouse
Entrez

50508

224480

Ensembl

ENSG00000074771

ENSMUSG00000023802

UniProt

Q9HBY0

Q672J9

RefSeq (mRNA)

NM_015718

NM_198958

RefSeq (protein)

NP_056533

NP_945196

Location (UCSC)Chr 6: 155.4 – 155.46 MbChr 17: 3.69 – 3.75 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

NADPH oxidase 3 is an enzyme that in humans is encoded by the NOX3 gene.[5][6]

Function

NADPH oxidases, such as NOX3, are plasma membrane-associated enzymes found in many cell types. They catalyze the production of superoxide by a 1-electron reduction of oxygen, using NADPH as the electron donor.[supplied by OMIM][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000074771 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000023802 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Cheng G, Cao Z, Xu X, van Meir EG, Lambeth JD (May 2001). "Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5". Gene. 269 (1–2): 131–40. doi:10.1016/S0378-1119(01)00449-8. PMID 11376945.
  6. 1 2 "Entrez Gene: NOX3 NADPH oxidase 3".

Further reading


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