NHLH1
Identifiers
AliasesNHLH1, HEN1, NSCL, NSCL1, bHLHa35, nescient helix-loop-helix 1
External IDsOMIM: 162360 MGI: 98481 HomoloGene: 4089 GeneCards: NHLH1
Orthologs
SpeciesHumanMouse
Entrez

4807

18071

Ensembl

ENSG00000171786

ENSMUSG00000051251

UniProt

Q02575
Q5T203

Q02576

RefSeq (mRNA)

NM_005598

NM_010916

RefSeq (protein)

NP_005589
NP_005589.1

NP_035046

Location (UCSC)Chr 1: 160.37 – 160.37 MbChr 1: 171.88 – 171.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Helix-loop-helix protein 1 is a protein that in humans is encoded by the NHLH1 gene.[5]

The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM][5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000171786 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000051251 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: NHLH1 nescient helix loop helix 1".

Further reading


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