NETO1
Identifiers
AliasesNETO1, BCTL1, BTCL1, neuropilin and tolloid like 1
External IDsOMIM: 607973 MGI: 2180216 HomoloGene: 16367 GeneCards: NETO1
Orthologs
SpeciesHumanMouse
Entrez

81832

246317

Ensembl

ENSG00000166342

ENSMUSG00000050321

UniProt

Q8TDF5

Q8R4I7

RefSeq (mRNA)

NM_144946
NM_001360910

RefSeq (protein)

NP_659195
NP_001347839

Location (UCSC)Chr 18: 72.74 – 72.87 MbChr 18: 86.39 – 86.51 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Neuropilin (NRP) and tolloid (TLL)-like 1 is a protein that in humans is encoded by the NETO1 gene.[5]

Function

This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in mice encodes a protein that plays a critical role in spatial learning and memory by regulating the function of synaptic N-methyl-D-aspartic acid receptor complexes in the hippocampus. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000166342 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000050321 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Neuropilin (NRP) and tolloid (TLL)-like 1".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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