NAPG
Identifiers
AliasesNAPG, GAMMASNAP, NSF attachment protein gamma
External IDsOMIM: 603216 MGI: 104561 HomoloGene: 2838 GeneCards: NAPG
Orthologs
SpeciesHumanMouse
Entrez

8774

108123

Ensembl

ENSG00000134265

ENSMUSG00000024581

UniProt

Q99747

Q9CWZ7

RefSeq (mRNA)

NM_003826

NM_028017

RefSeq (protein)

NP_003817

NP_082293

Location (UCSC)Chr 18: 10.53 – 10.55 MbChr 18: 63.11 – 63.13 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Gamma-soluble NSF attachment protein is a SNAP protein that in humans is encoded by the NAPG gene.[5][6]

Function

NSF and SNAPs (NSF attachment proteins) are general elements of the cellular membrane transport apparatus. The sequence of the predicted 312-amino acid human protein encoded by NAPG is 95% identical to that of bovine gamma-SNAP. NAPG mediates platelet exocytosis and controls the membrane fusion events of this process.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000134265 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024581 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Lemons PP, Chen D, Bernstein AM, Bennett MK, Whiteheart SW (Sep 1997). "Regulated secretion in platelets: identification of elements of the platelet exocytosis machinery". Blood. 90 (4): 1490–500. doi:10.1182/blood.V90.4.1490. PMID 9269766.
  6. 1 2 "Entrez Gene: NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma".

Further reading


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