There are several conditions of or affecting the human integumentary system that are associated with an increased risk of developing nonmelanoma skin cancer (i.e. squamous-cell carcinoma and basal-cell carcinoma).

Conditions of or affecting the human integumentary system associated with increased risk of nonmelanoma skin cancer
ConditionSquamous-cell carcinomaBasal-cell carcinoma
Xeroderma pigmentosum++
Oculocutaneous albinism++
Epidermodysplasia verruciformis+
Recessive dystrophic epidermolysis bullosa+
Ferguson–Smith syndrome+
Muir–Torre syndrome++
Nevoid basal cell carcinoma syndrome+
Bazex syndrome+
Rombo syndrome+
Discoid lupus erythematosus+
Erosive lichen planus+
Lichen sclerosus+
Porokeratosis+
Nevus sebaceous[note 1]+
Chronic non-healing wounds+
Seborrheic keratosis+

See also

Notes

  1. The most common benign neoplasm that may develop within a nevus sebaceous is a syringocystadenoma papilliferum, and the second most common is a trichoblastoma. The most common malignant neoplasm is a basal cell carcinoma.

References

Citations

    Sources

    • Bolognia, Jean L.; et al. (2007). Dermatology. St. Louis: Mosby. ISBN 1-4160-2999-0.
    • James, William D.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
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