Kenneth E. Wilzbach (October 14, 1920, Chicago – April 9, 2004, Bayside, California) was an American chemist, known for his contribution to biological and medical research through his development of tritium labelling in biological compounds.[1] The Wilzbach method is named in his honor.[2][3][4]

Biography

Wilzbach was born and raised in Chicago.[1] He graduated in chemistry from the University of Chicago with a bachelor's degree in 1940 and a Ph.D. in 1946. He joined Argonne National Laboratory in 1950[5] and worked there for forty years as a senior chemist.[1]

... Wilzbach worked on projects including tracer compounds and analyzing rocks before switching in 1976 to energy and environmental systems.[5]

He was one of five winners of the 1961 Ernest O. Lawrence Award; his award in the Life Sciences division was for "his development of tritium labeling of biologically important compounds, which have permitted major advances in biology and medicine."[6]

Wilzbach and his wife Eileen (née Marcin) had a 41-year marriage. She was born in 1924 and died in 1987. Upon his death he was survived by four sons, a daughter, nine grandchildren, and three great-grandchildren.[1]

Selected publications

  • Finholt, A. E.; Bond, A. C.; Wilzbach, K. E.; Schlesinger, H. I. (1947). "The Preparation and Some Properties of Hydrides of Elements of the Fourth Group of the Periodic System and of their Organic Derivatives". Journal of the American Chemical Society. 69 (11): 2692–2696. doi:10.1021/ja01203a041.
  • Barbaras, Glenn D.; Dillard, Clyde; Finholt, A. E.; Wartik, Thomas; Wilzbach, K. E.; Schlesinger, H. I. (1951). "The Preparation of the Hydrides of Zinc, Cadmium, Beryllium, Magnesium and Lithium by the Use of Lithium Aluminum Hydride". Journal of the American Chemical Society. 73 (10): 4585–4590. doi:10.1021/ja01154a025.
  • Wilzbach, Kenneth E. (1957). "Tritium-Labeling by Exposure of Organic Compounds to Tritium Gas". Journal of the American Chemical Society. 79 (4): 1013. doi:10.1021/ja01561a078. (over 900 citations)
  • Wilzbach, K. E.; Kaplan, Louis (1966). "A Photochemical 1,3 Cycloaddition of Olefins to Benzene". Journal of the American Chemical Society. 88 (9): 2066–2067. doi:10.1021/ja00961a052.
  • Wilzbach, K. E.; Ritscher, James S.; Kaplan, Louis. (1967). "Benzvalene, the Tricyclic Valence Isomer of Benzene". Journal of the American Chemical Society. 89 (4): 1031–1032. doi:10.1021/ja00980a053.
  • Wilzbach, Kenneth E.; Rausch, David J. (1970). "Photochemistry of nitrogen heterocycles. Dewar pyridine and its intermediacy in photoreduction and photohydration of pyridine". Journal of the American Chemical Society. 92 (7): 2178–2179. doi:10.1021/ja00710a088.

References

  1. 1 2 3 4 "Obituary. Wilzbach, Kenneth E." Chicago Tribune. April 13, 2004.
  2. ↑ "Wilzbach method". Oxford Reference.
  3. ↑ Steinberg, D.; Vaughan, M.; Anfinsen, C. B.; Gorry, J. (1957). "Preparation of Tritiated Proteins by the Wilzbach Method". Science. 126 (3271): 447–448. Bibcode:1957Sci...126..447S. doi:10.1126/science.126.3271.447. PMID 13467224.
  4. ↑ Angyal, S. J.; Fernandez, C. (1964). "Specific Tritium Labelling by the Wilzbach Method". Nature. 202 (4928): 176–177. Bibcode:1964Natur.202..176A. doi:10.1038/202176a0. S2CID 4286571.
  5. 1 2 "Alumni News, About Alumni, Deaths". University of Chicago Magazine. Vol. 96, no. 4. August 2004.
  6. ↑ "Kenneth E. Wilzbach, 1961". 1960s Laureates, Award Laureates, The Ernest O. Lawrence Award, Office of Science, U.S Department of Energy. 28 December 2010.
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