ERO1A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesERO1A, ERO1-alpha, ERO1LA, ERO1-L, ERO1-L-alpha, ERO1L, Ero1alpha, endoplasmic reticulum oxidoreductase alpha, endoplasmic reticulum oxidoreductase 1 alpha
External IDsOMIM: 615435 MGI: 1354385 HomoloGene: 49392 GeneCards: ERO1A
Orthologs
SpeciesHumanMouse
Entrez

30001

50527

Ensembl

ENSG00000197930

ENSMUSG00000021831

UniProt

Q96HE7

Q8R180

RefSeq (mRNA)

NM_014584

NM_015774

RefSeq (protein)

NP_056589

Location (UCSC)Chr 14: 52.64 – 52.7 MbChr 14: 45.52 – 45.56 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

ERO1-like protein alpha is a protein that in humans is encoded by the ERO1L gene.[5][6]


Interactions

ERO1L has been shown to interact with TXNDC4[7] and P4HB.[7][8]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000197930 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021831 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Cabibbo A, Pagani M, Fabbri M, Rocchi M, Farmery MR, Bulleid NJ, Sitia R (February 2000). "ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum". The Journal of Biological Chemistry. 275 (7): 4827–33. doi:10.1074/jbc.275.7.4827. PMID 10671517.
  6. "Entrez Gene: ERO1L ERO1-like (S. cerevisiae)".
  7. 1 2 Anelli T, Alessio M, Mezghrani A, Simmen T, Talamo F, Bachi A, Sitia R (February 2002). "ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family". The EMBO Journal. 21 (4): 835–44. doi:10.1093/emboj/21.4.835. PMC 125352. PMID 11847130.
  8. Mezghrani A, Fassio A, Benham A, Simmen T, Braakman I, Sitia R (November 2001). "Manipulation of oxidative protein folding and PDI redox state in mammalian cells". The EMBO Journal. 20 (22): 6288–96. doi:10.1093/emboj/20.22.6288. PMC 125306. PMID 11707400.

Further reading


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