TKFC
Identifiers
AliasesTKFC, NET45, DAK, triokinase and FMN cyclase, TKFCD
External IDsOMIM: 615844 MGI: 2385084 HomoloGene: 56710 GeneCards: TKFC
Orthologs
SpeciesHumanMouse
Entrez

26007

225913

Ensembl

ENSG00000149476

ENSMUSG00000034371

UniProt

Q3LXA3

Q8VC30

RefSeq (mRNA)

NM_145496

RefSeq (protein)

NP_663471

Location (UCSC)Chr 11: 61.33 – 61.35 MbChr 19: 10.57 – 10.58 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Triokinase/FMN cyclase is an enzyme that in humans is encoded by the DAK gene.[5]

Function

This gene is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4',5'-phosphate (aka cyclic FMN) from FAD. Several alternatively spliced transcript variants have been identified, but the full-length nature of only one has been determined.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000149476 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034371 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: DAK dihydroxyacetone kinase 2 homolog (S. cerevisiae)".

Further reading


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