Chlorozotocin
Haworth projection of chlorozotocin
Clinical data
ATC code
  • none
Identifiers
  • 2-{[(2-Chloroethyl)(nitroso)carbamoyl]amino}-2-deoxy-D-glucose
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC9H16ClN3O7
Molar mass313.69 g·mol−1
3D model (JSmol)
  • ClCCN(N=O)C(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO
  • InChI=1S/C9H16ClN3O7/c10-1-2-13(12-20)9(19)11-5(3-14)7(17)8(18)6(16)4-15/h3,5-8,15-18H,1-2,4H2,(H,11,19)/t5-,6+,7+,8+/m0/s1 ☒N
  • Key:MKQWTWSXVILIKJ-LXGUWJNJSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Chlorozotocin is a nitrosourea. It is used for cancer therapy.

The International Agency for Research on Cancer concluded it was "probably carcinogenic" in 1990[1]

It is an analogue of streptozotocin.[2]

References

  1. Humans, IARC Working Group on the Evaluation of Carcinogenic Risk to (1990). SUMMARY OF FINAL EVALUATIONS. International Agency for Research on Cancer.
  2. Wolfe MM (2006). Therapy of digestive disorders. Elsevier Health Sciences. p. 477. ISBN 978-1-4160-0317-5.


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