| KAT14 | |||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | KAT14, ATAC2, CRP2BP, PRO1194, dJ717M23.1, CSRP2BP, lysine acetyltransferase 14 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 617501 MGI: 1917264 HomoloGene: 10745 GeneCards: KAT14 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
CSRP2 binding protein is a protein that in humans is encoded by the CSRP2BP gene.[5]
CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse function. CSRP2 and some related proteins are thought to act as protein adapters, bridging two or more proteins to form a larger protein complex. The protein encoded by this gene binds to one of the LIM domains of CSRP2 and contains an acetyltransferase domain. Although the encoded protein has been detected in the cytoplasm, it is predominantly a nuclear protein. Alternatively spliced transcript variants have been described.[5]
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000149474 - Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000027425 - Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- 1 2 "Entrez Gene: CSRP2 binding protein". Retrieved 2011-09-20.
External links
- Human CSRP2BP genome location and CSRP2BP gene details page in the UCSC Genome Browser.
Further reading
Weiskirchen, R.; Gressner, A. M. (2000). "The Cysteine- and Glycine-Rich LIM Domain Protein CRP2 Specifically Interacts with a Novel Human Protein (CRP2BP)". Biochemical and Biophysical Research Communications. 274 (3): 655–663. doi:10.1006/bbrc.2000.3187. PMID 10924333. Wang, Y. -L.; Faiola, F.; Xu, M.; Pan, S.; Martinez, E. (2008). "Human ATAC is a GCN5/PCAF-containing Acetylase Complex with a Novel NC2-like Histone Fold Module That Interacts with the TATA-binding Protein". Journal of Biological Chemistry. 283 (49): 33808–33815. doi:10.1074/jbc.M806936200. PMC 2590711. PMID 18838386. Guelman, S.; Kozuka, K.; Mao, Y.; Pham, V.; Solloway, M. J.; Wang, J.; Wu, J.; Lill, J. R.; Zha, J. (2008). "The Double-Histone-Acetyltransferase Complex ATAC is Essential for Mammalian Development". Molecular and Cellular Biology. 29 (5): 1176–1188. doi:10.1128/MCB.01599-08. PMC 2643826. PMID 19103755. Wang, K.; Zhang, H.; Bloss, C. S.; Duvvuri, V.; Kaye, W.; Schork, N. J.; Berrettini, W.; Hakonarson, H. (2010). "A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa" (PDF). Molecular Psychiatry. 16 (9): 949–959. doi:10.1038/mp.2010.107. PMID 21079607. S2CID 15188506.