Bronidox
Names
Preferred IUPAC name
5-Bromo-5-nitro-1,3-dioxane
Other names
5-Bromo-5-nitro-m-dioxane
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.045.441
EC Number
  • 250-001-7
UNII
  • InChI=1S/C4H6BrNO4/c5-4(6(7)8)1-9-3-10-2-4/h1-3H2 checkY
    Key: XVBRCOKDZVQYAY-UHFFFAOYSA-N checkY
  • InChI=1/C4H6BrNO4/c5-4(6(7)8)1-9-3-10-2-4/h1-3H2
    Key: XVBRCOKDZVQYAY-UHFFFAOYAG
  • O=[N+]([O-])C1(Br)COCOC1
Properties
C4H6BrNO4
Molar mass 211.999 g·mol−1
Appearance White crystalline powder
Melting point 60 °C (140 °F; 333 K)[1]
58.5−62 °C[2]
insoluble
Hazards
GHS labelling:
GHS05: CorrosiveGHS07: Exclamation markGHS09: Environmental hazard
Danger
H302, H314, H315, H317, H410
P260, P261, P264, P270, P272, P273, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P332+P313, P333+P313, P362, P363, P391, P405, P501
Lethal dose or concentration (LD, LC):
590 mg/kg (mouse, oral)
455 mg/kg (rat, oral)
31 mg/kg (rat, ipr.)
2500 µg (mouse, skin)
2500 µg (rat, skin)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)
Infobox references

Bronidox, or 5-bromo-5-nitro-1,3-dioxane, is an antimicrobial chemical compound.

Bronidox causes inhibition of enzyme activity in bacteria.[3]

Bronidox is corrosive to metals.[4]

Uses

See also

References

  1. 5-BROMO-5-NITRO-1,3-DIOXANE Archived March 3, 2016, at the Wayback Machine, chemicalland21.com
  2. "Bronidox, Product Information Sheet" (PDF). Archived from the original (PDF) on September 29, 2007. Retrieved March 19, 2006.
  3. Ghannoum M, Thomson M, Bowman W, Al-Khalil S (1986). "Mode of action of the antimicrobial compound 5-bromo-5-nitro-1,3-dioxane (bronidox)". Folia Microbiol. (Praha). 31 (1): 19–31. doi:10.1007/BF02928676. PMID 3082729. S2CID 23920602.
  4. http://www.products.cognis.com/COGNIS/prodleaf.nsf/(SBU_Catalog)/FFAD30C61B67EFEB41256B4100427DD1/$File/BRONIDOX_r_L_5_E.pdf
  5. Archived December 21, 2004, at the Wayback Machine
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