BASP1
Identifiers
AliasesBASP1, CAP-23, CAP23, NAP-22, NAP22, brain abundant membrane attached signal protein 1
External IDsOMIM: 605940 MGI: 1917600 HomoloGene: 38168 GeneCards: BASP1
Orthologs
SpeciesHumanMouse
Entrez

10409

70350

Ensembl

ENSG00000176788

ENSMUSG00000045763

UniProt

P80723

Q91XV3

RefSeq (mRNA)

NM_006317
NM_001271606

NM_027395

RefSeq (protein)

NP_001258535
NP_006308

NP_081671

Location (UCSC)Chr 5: 17.07 – 17.28 MbChr 15: 25.36 – 25.41 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Brain acid soluble protein 1 is a protein that in humans is encoded by the BASP1 gene.[5][6][7]

This gene encodes a membrane bound protein with several transient phosphorylation sites and PEST motifs. Conservation of proteins with PEST sequences among different species supports their functional significance. PEST sequences typically occur in proteins with high turnover rates. Immunological characteristics of this protein are species specific. This protein also undergoes N-terminal myristoylation.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000176788 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000045763 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Mosevitsky MI, Capony JP, Skladchikova GYu, Novitskaya VA, Plekhanov AYu, Zakharov VV (Nov 1997). "The BASP1 family of myristoylated proteins abundant in axonal termini. Primary structure analysis and physico-chemical properties". Biochimie. 79 (6): 373–84. doi:10.1016/S0300-9084(97)80032-6. PMID 9310187.
  6. Park S, Kim YI, Kim B, Seong C, Oh Y, Baek K, Yoon J (Nov 1998). "Characterization of bovine and human cDNAs encoding NAP-22 (22 kDa neuronal tissue-enriched acidic protein) homologs". Mol Cells. 8 (4): 471–7. PMID 9749536.
  7. 1 2 "Entrez Gene: BASP1 brain abundant, membrane attached signal protein 1".

Further reading


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.