Amir Manbachi
NationalityIranian-Canadian
Alma materUniversity of Toronto
OccupationAcademic
Notable workTowards Ultrasound-guided Spinal Fusion Surgery (2018)

Amir Manbachi is an Iranian-Canadian academic and researcher.[1][2] He is the co-founder and current director of HEPIUS Innovation Lab at Johns Hopkins University.[3]

Biography

Manbachi is of Iranian descent.[3][2] He attended the University of Toronto, where he completed his bachelor's degree in applied sciences (BASc) in the Engineering Science (Physics) program.[4] Later, he obtained his master's degree and a PhD in biomedical engineering at the University of Toronto.[4][3][5] During his third year as a PhD candidate, he, along with his university advisers, established Spinesonics Medical which developed a sensor designed to aid in vertebral screw insertion procedures.[6][7] They received a $50,000 provincial grant to support their research and development efforts.[6]

In 2016, Manbachi joined the Department of Biomedical Engineering at Johns Hopkins University as a research faculty member.[4][8] At Johns Hopkins University, he co-founded HEPIUS Innovation Labs and now serves as its director.[9][10] He also served as an associate director of the Center for Bioengineering Innovation and Design.[11]

In 2018, Manbachi and Nao J. Gamo began researching ultrasound technology with the potential to target and "burn" brain tumors.[11] They received a total of $250,000 in grant funding from Hopkins, Maryland Technology Development Corp., and the Wallace H. Coulter Foundation for this purpose.[11]

In 2020, Manbachi and a team co-led by Nicholas Theodore at Johns Hopkins Medicine were awarded a $13.5M grant from the Defense Advanced Research Projects Agency (DARPA) to research wearable and implantable ultrasound technologies for spinal cord injury patients.[12][13]

In 2022, Manbachi received Baltimore Business Journal's 40 under 40 award, and secured a Johns Hopkins Discovery award.[3]

In 2023, the HEPIUS Innovation Lab at Hopkins, led by Manbachi, received a Food and Drug Administration Breakthrough Device Designation for a novel ultrasound imaging implant.[10][14]

Awards and recognition

  • 40 under 40 by Baltimore Business Journal[3]
  • University of Toronto's 2015 Inventor of the year award
  • Robert B. Pond Sr. Excellence in Teaching Excellence Award, Johns Hopkins University, Whiting School of Engineering[15]
  • Johns Hopkins Inst for Clinical and Translational Research’s KL2 Clinical Research Scholar, 2020
  • FDA Breakthrough designation pathway awarded to his MUSIC device invention, 2023

Selected publications

  • Manbachi A. and Cobbold R.S.C., 2011. Development and application of piezoelectric materials for ultrasound generation and detection. Ultrasound, 19(4), pp. 187–196.
  • Abramson HG, Curry EJ, Mess G, Thombre R, Kempski-Leadingham KM, Mistry S, Somanathan S, Roy L, Abu-Bonsrah N, Coles G, Doloff JC, Brem H, Theodore N, Huang J and Manbachi A (2022) Automatic detection of foreign body objects in neurosurgery using a deep learning approach on intraoperative ultrasound images: From animal models to first in-human testing. Front. Surg. 9:1040066. doi:10.3389/fsurg.2022.1040066
  • Aghabaglou F, Ainechi A, Abramson H, Curry E, Parvez Kaovasia T, Kamal S, Acord M, Mahapatra S, Pustavoitau A, Smith B, Azadi J, Son JK, Suk I, Theodore N, Tyler BM, Manbachi A. Ultrasound monitoring of microcirculation: An original study from the laboratory bench to the clinic. Microcirculation. 2022; 29: e12770. doi:10.1111/micc.12770
  • Kempksi Leadingham KM, Abramson HG, Perdomo-Pantoja A, Thombre R, Liu J, Norman M, Chavez F, Morrison K, Suk I, Gordon C, Armand M and Manbachi A. "Design of a Custom Flexible Ultrasound Transducer as an Implantable Cranial Sensor for Long-Term Post-Operative Monitoring of Brain Tumor Regrowth," 2022 IEEE International Ultrasonics Symposium (IUS), 2022, pp. 1–4, doi:10.1109/IUS54386.2022.9958345
  • Routkevitch D, Hersh AM, Kempski KM, Kerensky M, Theodore N, Thakor NV, Manbachi A, "FlowMorph: Morphological Segmentation of Ultrasound-Monitored Spinal Cord Microcirculation," 2022 IEEE Biomedical Circuits and Systems Conference (BioCAS), 2022, pp. 610–614, doi:10.1109/BioCAS54905.2022.9948639

Bibliography

  • Manbachi, Amir; M. Kempski Leadingham, Kelley; J. Curry, Eli (28 November 2022). The Abundant Promise of Ultrasound in Neurosurgery: A Broad Overview and Thoughts on Ethical Paths to Realizing Its Benefits. ISBN 9781510657250.
  • Manbachi, Amir (27 May 2018). Towards Ultrasound-guided Spinal Fusion Surgery. Springer International Publishing. ISBN 9783319806648.

References

  1. ↑ Staff, Daily Record (March 12, 2021). "Hopkins professors earn grants through Bisciotti Foundation Translational Fund".
  2. 1 2 "استاد ایرانی دانشگاه جانز هاپکینز: جامعه علمی باید از حق دفاع کند". صدای آمریکا. December 25, 2022.
  3. 1 2 3 4 5 "40 Under 40: Amir Manbachi, Johns Hopkins University".
  4. 1 2 3 "The path to a faculty position: Q & A with alumnus Amir Manbachi". Biomedical Engineering - University of Toronto. June 23, 2016.
  5. ↑ "Princely Persian performers". The Varsity. January 23, 2007.
  6. 1 2 "Job situation may get worse for Ontario graduates". The Canadian Press. September 11, 2013.
  7. ↑ Babbage, Maria (September 11, 2013). "Challenges just beginning for Ontario, Canada's most populous have-not province". CTVNews.
  8. ↑ "Trump fires acting AG over her stance not to enforce travel ban". Baltimore Sun. January 31, 2017.
  9. ↑ "Amir Manbachi".
  10. 1 2 "Johns Hopkins lab aiming to improve spinal cord injury care hits FDA milestone".
  11. 1 2 3 "Hopkins-born venture aims to use ultrasound technology to treat brain tumors".
  12. ↑ "Focused Ultrasound for Spinal Cord Injury: Johns Hopkins Receives Funding for New Device". October 30, 2020.
  13. ↑ "$13.48M Awarded to Johns Hopkins Scientists to Develop Implantable Ultrasound Devices for Patients with Spinal Cord Injury - Johns Hopkins Technology Ventures". ventures.jhu.edu. October 30, 2020.
  14. ↑ "Fire Awards 2023: HEPIUS Innovation Lab".
  15. ↑ "Amir Manbachi, Ph.D., M.Sc., Assistant Professor of Neurosurgery". Johns Hopkins Medicine.
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