telomere
See also: télomère
English
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Human chromosomes (grey) capped by telomeres (white)
Pronunciation
IPA(key): /ˈtɛləmɪəɹ/, /ˈtiːləmɪəɹ/
Noun
telomere (plural telomeres)
- (genetics) Either of the sequences of DNA at each end of a eukaryotic chromosome.
- 2004, Peter M. Lansdorp, 11: Telomeres and Telomere Regulation, Robert Paul Lanza (editor), Handbook of Stem Cells, Volume 2: Adult and Fetal Stem Cells, page 127,
- Chromosome ends or telomeres are composed of guanine-rich repeat sequences and associated proteins. A minimum number of repeats is essential for proper telomere function and to avoid sustained activation of DNA damage pathways that may result in replicative senescence or cell death.
- 2004, Peter M. Lansdorp, 11: Telomeres and Telomere Regulation, Robert Paul Lanza (editor), Handbook of Stem Cells, Volume 2: Adult and Fetal Stem Cells, page 127,
Related terms
Translations
either of the sequences of DNA at each end of a eukaryotic chromosome
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