synaptotoxicity

English

Etymology

synapto- +‎ toxicity

Noun

synaptotoxicity (countable and uncountable, plural synaptotoxicities)

  1. The condition of being synaptotoxic
    • 2015 November 6, “The mTOR Inhibitor Rapamycin Mitigates Perforant Pathway Neurodegeneration and Synapse Loss in a Mouse Model of Early-Stage Alzheimer-Type Tauopathy”, in PLOS ONE‎, →DOI:
      Compared with vehicle-treated controls, rapamycin protected against the tau-induced neuronal loss, synaptotoxicity, reactive microgliosis and astrogliosis, and activation of innate neuroimmunity.
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