prototrophy

prototrophy (usually uncountable, plural prototrophies)

1. The condition of being a prototroph
   • 1951 March, K. C. Atwood, “Periodic Selection in Escherichia Coli”, in Proceedings of the National Academy of Sciences of the United States of America, volume 37, number 3, page 146:

     Spontaneous mutations in bacteria are generally reversible. Consequently, in a medium where prototrophy confers no selective advantage, various auxotrophs (and other mutant types) should accumulate until for each type the number is such that the loss- by mutation to prototrophy should equal the gain by mutation to the corresponding auxotrophic condition.

   • 2015 August 22, “The Aspergillus fumigatus pkcA G579R Mutant Is Defective in the Activation of the Cell Wall Integrity Pathway but Is Dispensable for Virulence in a Neutropenic Mouse Infection Model”, in PLOS ONE‎, →DOI:

     The pyrG inserted into the gene replacement cassette was amplified from pCDA21 plasmid [40 ] and was used to generate a marker for prototrophy in the mutant strain.

• auxotrophy

• prototrophic

• trophotropy