motexafin

English

Etymology

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Noun

motexafin

  1. (medicine) an inhibitor of thioredoxin reductase and ribonucleotide reductase
    • 2016 March 2, “Brain Radiotherapy plus Concurrent Temozolomide versus Radiotherapy Alone for Patients with Brain Metastases: A Meta-Analysis”, in PLOS ONE‎, →DOI:
      The meta-analysis of Qin et al [12 ] confirmed that the combination of WBRT plus chemotherapy (including TMZ, carboplatin, and motexafin gadolinium) may increase treatment response rates in patients with BM, therefore TMZ combined with RT can be a reasonable treatment option for patients with BM. However, follow-up studies conclude that the addition of TMZ to RT does not improve survival and has an increased incidence of adverse events compared with RT alone [13 ,14 ].

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