minicolumnopathy

English

Etymology

minicolumn +‎ -o- +‎ -pathy

Noun

minicolumnopathy (plural minicolumnopathies)

  1. (neurology) An atypical presentation of minicolumns within the human brain.
    • 2007, Juan Martos Pérez, New Developments in Autism: The Future is Today‎, page 282:
      Brain size is therefore not a confound to the reported minicolumnopathy of autistic patients.
    • 2014, Manuel F. Casanova, “The Neuropathology of Autism”, in Fred R. Volkmar, Kevin A. Pelphrey, Rhea Paul, Sally J. Rogers, editors, Handbook of Autism and Pervasive Developmental Disorders, Volume 1: Diagnosis, Development, and Brain Mechanisms‎, page 518:
      The initial results suggesting a minicolumnopathy in autism have been reproduced in two independent samples.
    • 2020, Estate M. Sokhadze et al., “Psychological Markers of Arousal and Anxiety in Children with Autism Spectrum Disorder”, in Jane Johnson, Stephen M. Edelson, editors, Understanding and Treating Anxiety in Autism: A Multi-Disciplinary Approach‎, page 39:
      The analysis of the current state of research in this area is guided by theoretical concepts developed in our laboratory, namely the neurodevelopmental “minicolumnopathy” hypothesis of autism that predicts an abnormal E/I ratio, GABA deficits, and gamma oscillation abnormality in autism (Casanova et al., 2002, 2003, 2015, 2015).
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