hyperfractionation

International scientific vocabulary, from hyper- +‎ fractionation = hyper- +‎ fraction +‎ -ation.

• Rhymes: -eɪʃən

hyperfractionation (uncountable)

1. (radiotherapy) An especially highly divided form of fractionation: the division of a total dose of radiation into many small fractions.
   • 1983, H.D. Thames Jr, L.J. Peters, H.R. Withers, G.H. Fletcher, “Accelerated fractionation vs hyperfractionation: rationales for several treatments per day”, in International Journal of Radiation Oncology, Biology, Physics, volume 9, number 2, →DOI, →PMID, pages 127–138:

     Treatment with several doses per day offers the prospect of a significant therapeutic gain using readily available low LET beams. These regimens can be classified as either accelerated fractionation or hyperfractionation according to their rationales. With accelerated fractionation a conventional number of dose fractions is delivered in a significantly shortened overall treatment time in order to reduce the opportunity for tumor cell regeneration during treatment. With hyperfractionation, on the other hand, a large number of significantly reduced dose fractions is used to give a greater total dose in a conventional overall treatment time.

• fractionation

• fractionated
• hyperfractionated