cathelin

English

Etymology

Blend of cathepsin L + inhibitor, as coined in 1989.[1]

Noun

cathelin (uncountable)

  1. (biochemistry) The highly-conserved domain in all cathelicidin peptides
    • 2015 April 2, Babatunji Emmanuel Oyinloye et al., “Reactive Oxygen Species, Apoptosis, Antimicrobial Peptides and Human Inflammatory Diseases”, in Pharmaceuticals, volume 8, →DOI:
      Altogether, cathelicidins comprise an N-terminal cathelin domain and a C-terminal cationic antimicrobial domain, which is activated upon cleavage.

References

  1. Anka Ritonja, Majda Kopitar, Roman Jerala, Vito Turk (1989) “Primary structure of a new cysteine proteinase inhibitor from pig leucocytes”, in FEBS Letters, volume 255, number 2, →DOI, pages 211–214

Anagrams

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