B.1.617

Translingual

Alternative forms

  • B-1-617

Proper noun

B.1.617

  1. (virology) A virulent variant of the SARS-CoV-2 Coronavirus, which causes COVID-19; that has two significant mutations, E484Q and L452R, causing a wave of new infections in India in Spring 2021.
    • 2023, Laiali Alquraan, Karem H. Alzoubi, Suzie Y. Rababa'h, “Mutations of SARS-CoV-2 and their impact on disease diagnosis and severity”, in Informatics in medicine unlocked, →DOI:
      The dynamics, molecular interactions, and binding energy of the B.1.1.7 variant (spike N501Y mutant), B.1.617 variant (E484Q and L452R spike mutant), and wild-type (WT) were investigated recently in India using molecular dynamics simulations of three diverse spike-ACE2 complexes.
  2. (by extension) Synonym of B.1.617+, the group of sublineages derived from B.1.617 inclusive
    • 2023, Laiali Alquraan, Karem H. Alzoubi, Suzie Y. Rababa'h, “Mutations of SARS-CoV-2 and their impact on disease diagnosis and severity”, in Informatics in medicine unlocked, →DOI:
      Numerous variations of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), including D614G, B.1.1.7 (United Kingdom), B.1.1.28 (Brazil P1, P2), CAL.20C (Southern California), B.1.351 (South Africa), B.1.617 (B.1.617.1 Kappa & Delta B.1.617.2) and B.1.1.529, have been reported worldwide.

Synonyms

  • G/452R.V3
  • VOC-21APR
  • VUI-21APR

Hypernyms

virus

Hyponyms

  • B.1.617 (the original variant lineage)
  • B.1.617.1
  • B.1.617.2 (the sublineage prominent in the UK from early 2021)
  • B.1.617.3 (the first isolated variant sublineage)
  • VOC-21APR-02
  • VUI-21APR-01
  • VUI-21APR-02
  • VUI-21APR-03

Coordinate terms

(virus): (viral components)

  • E484Q (mutant E484)
  • L452R (mutant L452)
  • Q484
  • R452

Derived terms

virus
  • B.1.1.248 (Brazilian precursor strain to P.1 and P.2)
  • B.1.1.28 (Brazilian parent strain to P.1 and P.2)
  • B.1.1.28.1 ("P.1" Manaus [Brazil] variant)
  • B.1.1.28.2 ("P.2" Rio de Janeiro variant)
  • B.1.1.7 (Kent [UK, British] variant)
  • B.1.351 (South African variant)

Descendants

  • English: lineage B.1.617
  • English: B.1.617 lineage

Translations

Further reading

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