Escitalopram

Escitalopram is an antidepressant medication. It is used as a drug to help treat depression, obsessive-compulsive disorder, social anxiety disorder and other mental illnesses. It is commonly known and sold as Lexapro or Cipralex.[1]

Escitalopram
Clinical data
Pronunciationaudio speaker iconpronunciation 
Trade namesCipralex, Lexapro, others
AHFS/Drugs.comMonograph
MedlinePlusa603005
License data
Pregnancy
category
  • AU: C
Routes of
administration		By mouth
Drug classSelective serotonin reuptake inhibitor
ATC code
Legal status
Legal status
  • AU: S4 (Prescription only)
  • CA: ℞-only
  • UK: POM (Prescription only)
  • US: ℞-only
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability80%
Protein binding~56%
MetabolismLiver, specifically the enzymes CYP3A4 and CYP2C19
Elimination half-life27–32 hours
Identifiers
IUPAC name
  • (S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
ECHA InfoCard100.244.188
Chemical and physical data
FormulaC20H21FN2O
Molar mass324.392 g/mol
(414.43 as oxalate)
3D model (JSmol)
SMILES
  • Fc1ccc(cc1)[C@@]3(OCc2cc(C#N)ccc23)CCCN(C)C
InChI
  • InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3/t20-/m0/s1 checkY
  • Key:WSEQXVZVJXJVFP-FQEVSTJZSA-N checkY
 ☒NcheckY (what is this?)  (verify)
Escitalopram pills

Side Effects

Escitalopram can cause sleeping problems, dry mouth and diarrhea. It can also cause sexual problems.[2] These sexual problems usually disappear after a person stops using the drug. However, in some cases these problems can last for months or years.

References
  1. Lexapro article
  2. Lexapro prescribing information


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