RPS11
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRPS11, S11, ribosomal protein S11
External IDsOMIM: 180471 MGI: 1351329 HomoloGene: 88443 GeneCards: RPS11
Orthologs
SpeciesHumanMouse
Entrez

6205

27207

Ensembl

ENSG00000142534

ENSMUSG00000003429

UniProt

P62280

P62281

RefSeq (mRNA)

NM_001015

NM_013725

RefSeq (protein)

NP_001006

NP_038753

Location (UCSC)Chr 19: 49.5 – 49.5 MbChr 7: 44.77 – 44.77 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

40S ribosomal protein S11 is a protein that in humans is encoded by the RPS11 gene.[5][6][7]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S17) is thought to be involved in the recognition of termination codons. This gene is co-transcribed with a small nucleolar RNA gene, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000142534 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000003429 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Feo S, Davies B, Fried M (Jun 1992). "The mapping of seven intron-containing ribosomal protein genes shows they are unlinked in the human genome". Genomics. 13 (1): 201–7. doi:10.1016/0888-7543(92)90221-D. PMID 1577483.
  6. Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.
  7. 1 2 "Entrez Gene: RPS11 ribosomal protein S11".

Further reading

  • Overview of all the structural information available in the PDB for UniProt: P62280 (40S ribosomal protein S11) at the PDBe-KB.
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