Mother of Cities may refer to:
- Mecca, is the capital of Mecca Province in western Saudi Arabia, the holiest city in Islam, and is referenced in The Holy Quran as the 'mother of cities'. See Quran 47:7.
- AsunciĆ³n, capital and largest city of Paraguay.
- Balkh, among the oldest cities of Afghanistan.
- Prague, capital and largest city of the Czech Republic.
- Santiago del Estero, oldest city of Argentina.
See also
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