lysosomal trafficking regulator
Identifiers
SymbolLYST
Alt. symbolsCHS1
NCBI gene1130
HGNC1968
OMIM606897
RefSeqNM_000081
UniProtQ99698
Other data
LocusChr. 1 q42.1-42.2
Search for
StructuresSwiss-model
DomainsInterPro

Lysosomal trafficking regulator is a vesicular transport protein associated with Chédiak–Higashi syndrome.

In melanocytic cells LYST gene expression may be regulated by MITF.[1]

References

  1. Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971.


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